Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.4
USERS' SCORE
Good
Based on 9 Reviews
8.3
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Thiamin (B1 from culture of S.cerevisiae)
5 mg
417%
Riboflavin (B2 from culture of S. cerevisiae)
10 mg
769%
Niacin (as Niacinamide from culture of S. cerevisiae)
45 mg
281%
Vitamin B6 (from culture of S. cerevisiae)
10 mg
588%
Folate (from culture of S. cerevisiae)
450 mcg DFE
113%
Vitamin B12 (as Methylcobalamin from culture of S. cerevisiae)
133 mcg
5542%
Biotin (from culture of S. cerevisiae)
325 mcg
1083%
Pantothenic Acid (from culture of S. cerevisiae)
45 mg
900%
RAW Organic Fruit & Vegetable Blend
360 mg
+
RAW Probiotic & Enzyme Blend
60 mg
+
Top Medical Research Studies
9
We explored how vitamin B6 (VB6) supports heart recovery post-heart attack. In our study, we found that VB6 encourages angiogenesis, which is crucial for healing. Through experiments, we noticed that VB6 helps in cell migration and blood vessel formation by activating a specific protein that plays a key role in these processes. Additionally, long-term use of VB6 improved heart function in mice. While these findings are promising, it’s important to note that further research is necessary to fully understand VB6's effects in humans.
Read More
9
We looked into whether vitamin B-6 could help prevent heart failure with preserved ejection fraction (HFpEF) in a mouse model. By using a high-fat diet and other supplements, we created conditions for HFpEF and tested the effects of vitamin B-6 on cardiac function.
The results showed that co-administering vitamin B-6 improved heart function and reduced harmful phenotypic changes in heart macrophages. However, these benefits disappeared in mice lacking a specific protein called DOK3. Overall, vitamin B-6 appears to help mitigate HFpEF by supporting DOK3 signaling and inhibiting detrimental macrophage changes.
The results showed that co-administering vitamin B-6 improved heart function and reduced harmful phenotypic changes in heart macrophages. However, these benefits disappeared in mice lacking a specific protein called DOK3. Overall, vitamin B-6 appears to help mitigate HFpEF by supporting DOK3 signaling and inhibiting detrimental macrophage changes.
Read More
8
We explored the impact of long-term vitamin B1 (VB1) maintenance on heart failure (HF) outcomes through a study involving 88 patients. These patients were divided into three groups based on their VB1 levels: a control group with normal levels, a group receiving short-term supplementation, and a group focused on long-term maintenance of normal levels.
The results showed that those who maintained normal VB1 levels experienced better health outcomes compared to those in the other groups. Our findings indicate that consistent VB1 management could be crucial for enhancing HF therapy and reducing risks of hospitalization and cardiovascular death.
The results showed that those who maintained normal VB1 levels experienced better health outcomes compared to those in the other groups. Our findings indicate that consistent VB1 management could be crucial for enhancing HF therapy and reducing risks of hospitalization and cardiovascular death.
Read More
Most Useful Reviews
9
Improves vitality
24 people found this helpful
This vitamin complex has been a game-changer for me. After taking it for two months, I feel invigorated and energetic, better managing fatigue and stress. I only need one capsule daily, as it digests well. It's certainly the most effective vitamin B complex I've tried, helping me feel more balanced and enhancing my mood. I will continue to purchase this.
Read More
9
Supports nerve health
7 people found this helpful
I trust this brand for its B vitamins. They are fantastic for heart and nerve health, dissolving easily in water. Taking them on an empty stomach optimises their benefits.
Read More
9
Regulates blood sugar
2 people found this helpful
I’ve given this complex to my father, who has diabetes and hypertension. Since he started taking it, his blood sugar and blood pressure have stabilised. I appreciate that it’s a raw vitamin, setting it apart from others. It's particularly effective for his needs.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.4
- All Researches
9
We explored how vitamin B6 (VB6) supports heart recovery post-heart attack. In our study, we found that VB6 encourages angiogenesis, which is crucial for healing. Through experiments, we noticed that VB6 helps in cell migration and blood vessel formation by activating a specific protein that plays a key role in these processes. Additionally, long-term use of VB6 improved heart function in mice. While these findings are promising, it’s important to note that further research is necessary to fully understand VB6's effects in humans.
Read More
9
We looked into whether vitamin B-6 could help prevent heart failure with preserved ejection fraction (HFpEF) in a mouse model. By using a high-fat diet and other supplements, we created conditions for HFpEF and tested the effects of vitamin B-6 on cardiac function.
The results showed that co-administering vitamin B-6 improved heart function and reduced harmful phenotypic changes in heart macrophages. However, these benefits disappeared in mice lacking a specific protein called DOK3. Overall, vitamin B-6 appears to help mitigate HFpEF by supporting DOK3 signaling and inhibiting detrimental macrophage changes.
The results showed that co-administering vitamin B-6 improved heart function and reduced harmful phenotypic changes in heart macrophages. However, these benefits disappeared in mice lacking a specific protein called DOK3. Overall, vitamin B-6 appears to help mitigate HFpEF by supporting DOK3 signaling and inhibiting detrimental macrophage changes.
Read More
8
We investigated how a specific gene variation (MTHFR C677T) influences the outcome for patients with coronary heart disease and hypertension receiving folic acid and enalapril.
Over 540 patients were studied, dividing them into groups that received folic acid or standard treatment.
Our results revealed that patients who took folic acid had better outcomes, including lower rates of cardiovascular events, compared to those who did not. This indicates that folic acid supplementation may enhance treatment success for these high-risk patients.
Over 540 patients were studied, dividing them into groups that received folic acid or standard treatment.
Our results revealed that patients who took folic acid had better outcomes, including lower rates of cardiovascular events, compared to those who did not. This indicates that folic acid supplementation may enhance treatment success for these high-risk patients.
Read More
8
In our exploration of TANGO2-deficiency disorder, we found that cardiac arrhythmias linked to this genetic condition are often resistant to standard treatments.
Using innovative patient-derived stem cell models, we identified that high doses of folate (vitamin B9) can significantly reduce arrhythmias.
Clinical data also indicated that multivitamin and B complex intake may lower the risk of serious heart issues in affected individuals.
This suggests that B vitamins might offer a life-saving strategy for managing dangerous cardiac events in patients with this disorder.
Using innovative patient-derived stem cell models, we identified that high doses of folate (vitamin B9) can significantly reduce arrhythmias.
Clinical data also indicated that multivitamin and B complex intake may lower the risk of serious heart issues in affected individuals.
This suggests that B vitamins might offer a life-saving strategy for managing dangerous cardiac events in patients with this disorder.
Read More
8
We explored the impact of long-term vitamin B1 (VB1) maintenance on heart failure (HF) outcomes through a study involving 88 patients. These patients were divided into three groups based on their VB1 levels: a control group with normal levels, a group receiving short-term supplementation, and a group focused on long-term maintenance of normal levels.
The results showed that those who maintained normal VB1 levels experienced better health outcomes compared to those in the other groups. Our findings indicate that consistent VB1 management could be crucial for enhancing HF therapy and reducing risks of hospitalization and cardiovascular death.
The results showed that those who maintained normal VB1 levels experienced better health outcomes compared to those in the other groups. Our findings indicate that consistent VB1 management could be crucial for enhancing HF therapy and reducing risks of hospitalization and cardiovascular death.
Read More
User Reviews
USERS' SCORE
Good
Based on 9 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Improves vitality
24 people found this helpful
This vitamin complex has been a game-changer for me. After taking it for two months, I feel invigorated and energetic, better managing fatigue and stress. I only need one capsule daily, as it digests well. It's certainly the most effective vitamin B complex I've tried, helping me feel more balanced and enhancing my mood. I will continue to purchase this.
Read More
9
Supports nerve health
7 people found this helpful
I trust this brand for its B vitamins. They are fantastic for heart and nerve health, dissolving easily in water. Taking them on an empty stomach optimises their benefits.
Read More
9
Regulates blood sugar
2 people found this helpful
I’ve given this complex to my father, who has diabetes and hypertension. Since he started taking it, his blood sugar and blood pressure have stabilised. I appreciate that it’s a raw vitamin, setting it apart from others. It's particularly effective for his needs.
Read More
7.5
Boosts energy effectively
These B vitamins have positively impacted my energy and metabolism, aiding my heart health. I typically swallow the capsule, so I'm unsure of its taste, but the potency is excellent. The packaging was also impressive upon delivery.
Read More
9
Normalises heart rhythm
29 people found this helpful
My friend introduced me to these vitamins when I was struggling with tachycardia. After taking just a few capsules alongside selenium, my heart rate returned to normal. I now use these vitamins regularly for stress management, and they work effectively. This complex has truly transformed my health, and I’m glad to share my experience as it might help others.
Read More
Frequently Asked Questions
9
Improves vitality
24 people found this helpful
This vitamin complex has been a game-changer for me. After taking it for two months, I feel invigorated and energetic, better managing fatigue and stress. I only need one capsule daily, as it digests well. It's certainly the most effective vitamin B complex I've tried, helping me feel more balanced and enhancing my mood. I will continue to purchase this.
9
Regulates blood sugar
2 people found this helpful
I’ve given this complex to my father, who has diabetes and hypertension. Since he started taking it, his blood sugar and blood pressure have stabilised. I appreciate that it’s a raw vitamin, setting it apart from others. It's particularly effective for his needs.
9
Normalises heart rhythm
29 people found this helpful
My friend introduced me to these vitamins when I was struggling with tachycardia. After taking just a few capsules alongside selenium, my heart rate returned to normal. I now use these vitamins regularly for stress management, and they work effectively. This complex has truly transformed my health, and I’m glad to share my experience as it might help others.
7.5
Eases bodily pain
1 people found this helpful
The quality of these Vitamins B Complex is exceptional. After experiencing numbness and pain on one side of my body, I noticed significant relief since starting these vitamins. They have alleviated my discomfort and improved my overall health, contributing positively to my nerve health.
7.5
Boosts energy effectively
These B vitamins have positively impacted my energy and metabolism, aiding my heart health. I typically swallow the capsule, so I'm unsure of its taste, but the potency is excellent. The packaging was also impressive upon delivery.
7.5
Boosts energy levels
36 people found this helpful
Thank you, iHerb. I’m very pleased with this complex. It provides strength and energy. After a stressful day, I took an extra capsule and felt revitalised. It has benefited my entire family, with remarkable results. B12 supports DNA synthesis and prevents deficiencies that can affect the nervous system, leading to issues such as heart disease. Other vitamins in the complex contribute to various processes essential for health, including metabolism. I recommend it for anyone needing an energy boost.
2
Ineffective for digestion
1 people found this helpful
The composition of these vitamins is commendable. However, I have Crohn's disease, and they did not work for me as my body couldn't absorb them effectively. I was disappointed as my haemoglobin levels did not improve. If digestive absorption is an issue, I recommend seeking alternatives.
9
We explored how vitamin B6 (VB6) supports heart recovery post-heart attack. In our study, we found that VB6 encourages angiogenesis, which is crucial for healing. Through experiments, we noticed that VB6 helps in cell migration and blood vessel formation by activating a specific protein that plays a key role in these processes. Additionally, long-term use of VB6 improved heart function in mice. While these findings are promising, it’s important to note that further research is necessary to fully understand VB6's effects in humans.
8
We investigated how a specific gene variation (MTHFR C677T) influences the outcome for patients with coronary heart disease and hypertension receiving folic acid and enalapril.
Over 540 patients were studied, dividing them into groups that received folic acid or standard treatment.
Our results revealed that patients who took folic acid had better outcomes, including lower rates of cardiovascular events, compared to those who did not. This indicates that folic acid supplementation may enhance treatment success for these high-risk patients.
Over 540 patients were studied, dividing them into groups that received folic acid or standard treatment.
Our results revealed that patients who took folic acid had better outcomes, including lower rates of cardiovascular events, compared to those who did not. This indicates that folic acid supplementation may enhance treatment success for these high-risk patients.
9
We looked into whether vitamin B-6 could help prevent heart failure with preserved ejection fraction (HFpEF) in a mouse model. By using a high-fat diet and other supplements, we created conditions for HFpEF and tested the effects of vitamin B-6 on cardiac function.
The results showed that co-administering vitamin B-6 improved heart function and reduced harmful phenotypic changes in heart macrophages. However, these benefits disappeared in mice lacking a specific protein called DOK3. Overall, vitamin B-6 appears to help mitigate HFpEF by supporting DOK3 signaling and inhibiting detrimental macrophage changes.
The results showed that co-administering vitamin B-6 improved heart function and reduced harmful phenotypic changes in heart macrophages. However, these benefits disappeared in mice lacking a specific protein called DOK3. Overall, vitamin B-6 appears to help mitigate HFpEF by supporting DOK3 signaling and inhibiting detrimental macrophage changes.
8
In our exploration of TANGO2-deficiency disorder, we found that cardiac arrhythmias linked to this genetic condition are often resistant to standard treatments.
Using innovative patient-derived stem cell models, we identified that high doses of folate (vitamin B9) can significantly reduce arrhythmias.
Clinical data also indicated that multivitamin and B complex intake may lower the risk of serious heart issues in affected individuals.
This suggests that B vitamins might offer a life-saving strategy for managing dangerous cardiac events in patients with this disorder.
Using innovative patient-derived stem cell models, we identified that high doses of folate (vitamin B9) can significantly reduce arrhythmias.
Clinical data also indicated that multivitamin and B complex intake may lower the risk of serious heart issues in affected individuals.
This suggests that B vitamins might offer a life-saving strategy for managing dangerous cardiac events in patients with this disorder.
8
We explored the impact of long-term vitamin B1 (VB1) maintenance on heart failure (HF) outcomes through a study involving 88 patients. These patients were divided into three groups based on their VB1 levels: a control group with normal levels, a group receiving short-term supplementation, and a group focused on long-term maintenance of normal levels.
The results showed that those who maintained normal VB1 levels experienced better health outcomes compared to those in the other groups. Our findings indicate that consistent VB1 management could be crucial for enhancing HF therapy and reducing risks of hospitalization and cardiovascular death.
The results showed that those who maintained normal VB1 levels experienced better health outcomes compared to those in the other groups. Our findings indicate that consistent VB1 management could be crucial for enhancing HF therapy and reducing risks of hospitalization and cardiovascular death.
References
- Wang XQ, Yin S, Wang QW, Bai WW, Tan RH, et al. Vitamin B6 allosterically activates AMPK to promote postischemic angiogenesis in mice. Eur J Pharmacol. 2025;993:177413. doi:10.1016/j.ejphar.2025.177413
- Ma L, Zeng L, Wang X. MTHFR C677T gene polymorphism in patients with coronary heart disease and hypertension treated with enalapril and folic acid: implications for prognosis. Cell Mol Biol (Noisy-le-grand). 2024;70:142. doi:10.14715/cmb/2024.70.9.20
- Song JW, Zhang ZS, Chen L, Wang QW, Xu JY, et al. Vitamin B-6 Prevents Heart Failure with Preserved Ejection Fraction Through Downstream of Kinase 3 in a Mouse Model. J Nutr. 2024;154:3031. doi:10.1016/j.tjnut.2024.08.006
- Xu W, Cao Y, Stephens SB, Arredondo MJ, Chen Y, et al. Folate as a potential treatment for lethal ventricular arrhythmias in TANGO2-deficiency disorder. JCI Insight. 2024;9. doi:10.1172/jci.insight.171005
- Morimoto J, Satogami K, Naraoka T, Taruya A, Tanaka A. Long-Term Maintenance of Normal Serum Vitamin B Levels Is Associated with Better Outcomes in Patients with Heart Failure. Int Heart J. 2024;65:458. doi:10.1536/ihj.23-550
